"Anopheles stephensi ; Kelch13 ; Plasmodium falciparum ; artemisinin combination therapies (ACTs); gametocytes; multidrug-resistant malaria; transmission blocking"

Transmission of Artemisinin-Resistant Malaria Parasites to Mosquitoes under Antimalarial Drug Pressure

Resistance to artemisinin-based combination therapy (ACT) in the Plasmodium falciparum parasite is threatening to reverse recent gains in reducing global deaths from malaria. While resistance manifests as delayed parasite clearance in patients, the …